Programação ISZB

8:00 – 8:30	Registration ISZB Registration
8:30 – 9:00	Welcome ISZB Welcome
9:00 – 10:00	Plenary 1 Michal Hershfinkel Zn2+ Acts as a First Messenger via the Zinc Sensing Receptor
10:00 – 10:30	Coffee Break
10:30 – 10:55	Zinc Signaling in Cancer Ling Huang Determine the role of zinc transporter SLC39A10 in pancreatic cancer
10:55 – 11:20	Zinc Signaling in Cancer Oleh Khalimonchuk Mitochondrial zinc metallopeptidase OMA1 as a new therapeutic target in treatment-refractory breast cancer
11:20 – 11:45	Zinc Signaling in Cancer Zakeya Baalawy An investigation to determine the role of zinc and ZIP family metal transporters in Renal Cell Carcinoma
11:45 – 12:00	Panel Discussion
12:00 – 13:30	Lunch
13:30 – 13:55	Zinc in Immunity Daren Knoell Zinc Dyshomeostasis Alters the Gut Microbiome Causing Metabolic Disruption of Macrophage-Mediated Bacterial Clearance in the Lung
13:55 – 14:20	Zinc in Immunity Stefan Feske Different ZIP transporters control CD4 T cell function in autoimmunity and immunity to infection
14:20 – 14:45	Zinc in Immunity Matthew Sweet Understanding and manipulating the antibacterial zinc toxicity response in macrophages for anti-infective design
14:45 – 15:00	Panel Discussion
15:00 – 15:30	Coffee Break
15:30 – 15:55	Zinc in Neurobiology Richard Dyck Vesicular zinc modulates postnatal hippocampal neurogenesis and experience-dependent plasticity
15:55 – 16:20	Zinc in Neurobiology Charles Anderson The roles of the zinc transporter proteins ZnT3 and ZIP12 in synaptic function and synaptic structure in the mouse auditory cortex.
16:20 – 16:30	Panel Discussion
16:30 – 16:55	Zinc Imaging and Biosensors Carlos Tejeda-Guzman Zinc chelation induces visible pigment granules and loss of autofluorescence in Drosophila Malpighian tubules
16:55 – 17:20	Zinc Imaging and Biosensors Wen-hong Li A versatile fluorescent zinc indicator, ZIGIR-2, for imaging zinc rich vesicles in living cells
17:20 – 17:30	Panel Discussion
18:00 – 20:00	Opening Ceremony Opening Ceremony
20:00 – 22:00	Cocktail Opening Cocktail Reception

8:30 – 9:30	Business Meeting ISZB Business Meeting
9:30 – 10:00	Coffee Break
10:00 – 10:25	Zinc Transporters Yuta Amagai Roles of Zinc Transporters in Maintaining ER and Golgi Zinc Homeostasis
10:25 – 10:50	Zinc Transporters Zhi Luo Recent progress in the regulation of zinc metabolism and homeostasis in the vertebrates
10:50 – 11:15	Zinc Transporters Fudi Wang Transporters and Zincology: Decoding Zinc Homeostasis in Health and Disease
11:15 – 11:30	Panel Discussion
11:30 – 12:15	Coffee Break / Lunch
12:15 – 12:30	Trainee Session 1 Emma Dalton Ramping up macrophage antibacterial zinc toxicity to combat antibiotic resistant bacterial infections
12:30 – 12:45	Trainee Session 1 Braden Rue A high-affinity sensor mitoGZnP4s uncovers a TRPML1-MCU axis governing mitochondrial Zn2+ uptake
12:45 – 13:00	Trainee Session 1 Xiujuan Tong Real-time Visualization and Quantification of Zinc Dynamics in Live Zebrafish using a Novel FRET-based Probe
13:00 – 13:15	Trainee Session 1 Weronika Leszczynska Characteristics of interaction of zinc and copper ions with human metallothioneins (MT1a-MT4)
13:15 – 13:30	Trainee Session 1 Sergio Neto Impacts of excess zinc on the Chromobacterium violaceum transcriptome revealed by RNAseq analysis
13:30 – 14:00	Short Break
14:00 – 19:30	Cultural Tour Cultural Tour (Buses depart at 2:00 pm. Boxed lunches on bus.)
19:30 – 22:00	Congress Dinner Congress Dinner

9:00 – 10:00	Plenary 3 Toshiyuki Fukada From Cytokine to Zinc Biology: New Insights into Zinc Transporters' Function, Disease, and Drug Development
10:00 – 10:30	Coffee Break
10:30 – 10:55	Zinc in Development and Reproduction Christer Hogstrand The membrane androgen receptor, ZIP9, regulates the hypothalamic-pituitary-gonadal (HPG) axis and is essential for female fertility in zebrafish
10:55 – 11:20	Zinc in Development and Reproduction Fanis Missirlis Physiological relevance of prominent zinc storage granules in the Malpighian Tubules of Drosophila melanogaster larvae.
11:20 – 11:45	Zinc in Development and Reproduction Satoshi Takenaka Pathophysiological Significance of Impaired KAT7-Dependent Histone H3K14 Acetylation During Zinc Deficiency
11:45 – 12:00	Panel Discussion
12:00 – 13:00	Lunch
13:00 – 13:25	Zinc in Human Health, Disease, and Aging Christopher Elitt Gene transcripts in plasma exosomes for specific zinc transporters and metallothioneins are downregulated in human preterm infants
13:25 – 13:50	Zinc in Human Health, Disease, and Aging Andrew Hall Zinc Complexed with Lysine and Glutamic Acid: Effects on Intestinal Zinc Absorption and Utilization in Adult Volunteers, a Research Update
13:50 – 14:15	Zinc in Human Health, Disease, and Aging Samantha Pitt Altered Zn2+ homeostasis in Niemann-Pick C1 disease results in impaired NAADP-mediated lysosomal Ca2+- dynamics
14:15 – 14:40	Zinc in Human Health, Disease, and Aging Artur Krezel Silver ions detroy zinc fingers, but glutathione comes the rescue
14:40 – 15:00	Panel Discussion
15:00 – 15:30	Coffee Break
15:30 – 15:45	Trainee Session 2 Oscar Antonio Nunez-Gaytan The possible involvement of serotonin in regulating zinc homeostasis
15:45 – 16:00	Trainee Session 2 Raul Jorge-Marrero Effect of subcutaneous kynurenine injection on systemic zinc regulation in murine models
16:00 – 16:15	Trainee Session 2 Georgia Farr Novel roles for ZIP7 in metastasis-associated behaviours of breast cancer
16:15 – 16:30	Trainee Session 2 Yahav Ishay ZnR/GPR39 as a Developmental Timekeeper of Hippocampal Neurons
16:30 – 17:00	Coffee Break
17:00 – 18:30	Poster Session Martyna Uscila Biophysical and Biochemical Characterization of Human Metallothionein MT1HL1 Zuzanna Janiec Zn(II)-induced homodimerization of C-terminal cysteine cluster of MTF-1 transcription factor Kevy Shu-Leung Lai Zinc Deficiency at ICU Admission: Longitudinal Trends and Diagnostic Stratification Sang Won Suh Transcranial Focused Ultrasound Enhances Adult Hippocampal Neurogenesis via Vesicular Zinc Signaling Kaitlin Bainer Investigating the roles of synaptic zinc in inhibitory neurotransmission in the mouse auditory cortex Yahav Ishay ZnR/GPR39 as a Developmental Timekeeper of Hippocampal Neurons Oscar Antoni Nunez-Gaytan The possible involvement of serotonin in regulating zinc homeostasis Rayli Ruby Synaptic zinc contributes to AMPA receptor maturation in the mouse auditory cortex Emma Trate The discovery and refinement of small molecule compounds that can act as ZIP12 agonists and antagonists Raul Jorge-Marrero Effect of subcutaneous kynurenine injection on systemic zinc regulation in murine models Deeksha Pal Functional Role of ZIP10-Mediated Zinc Signalling in Renal Cell Carcinoma: Evidence from Human Tissues and Genetically Modified Mice Cynthia Sarai Sanchez-Gonazalez How does Rab32 function in the biogenesis of zinc storage granules?
18:30 – 18:55	Zinc Biogenics and Genetics Sangyong Choi A Common Genetic Variant Near the PPCDC Gene Regulates the Cellular Zinc Homeostasis.
18:55 – 19:20	Zinc Biogenics and Genetics Sunita Ho Zinc signatures inform site-specific pathways of kidney stone formation
19:20 – 19:30	Panel Discussion
19:30 – 20:00	Award Presentations Award Presentations
20:00 – 22:00	Social Meeting Social Meeting

9:00 – 10:00	Plenary 4 · Frederickson Prize Lothar Rink Zinc in Immunosenescence and Malnutrition
10:00 – 10:30	Coffee Break
10:30 – 10:55	Zinc in Host / Pathogen Dynamics Derrick Samuelson Microbiota-derived metallophores contribute to IBD severity
10:55 – 11:20	Zinc in Host / Pathogen Dynamics Divya Ramnath Harnessing Zinc Toxicity Pathways to Overcome Antimicrobial Resistance
11:20 – 11:45	Zinc in Host / Pathogen Dynamics Eusondia Arnett Mycobacterium tuberculosis subverts macrophage-mediated defense through exploitation of the Zn transporter ZIP8
11:45 – 12:00	Panel Discussion
12:00 – 13:00	Closing Session Closing Session